Breadcrumb Home > Dictionary > Index C calmative: Meaning and Definition of Find definitions for: calm•a•tive Pronunciation: (kä'mu-tiv, kal'mu-), [key] — Med. Med. —adj. having a sedative effect. —n. a calmative agent. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. calm calmodulin ✖ Related Content Daily Word Quiz: careening Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language