Breadcrumb Home > Thesaurus > W Synonyms of wayne Find synonyms for: Noun1. Wayne, John Wayne, Duke Wayneusage: United States film actor who played tough heroes (1907-1979)2. Wayne, Anthony Wayne, Mad Anthony Wayneusage: American general during the American Revolution (1745-1796)WordNet 3.0 Copyright © 2006 by Princeton University. All rights reserved.Definition and meaning of wayne (Dictionary) ✖ Related Content Daily Word Quiz: legerdemain Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language