Schick test, diagnostic test designed to evaluate susceptibility to diphtheria . A small amount of diphtheria toxin is injected into the skin; the injection will produce an area of redness and swelling in individuals with low levels of antibody (i.e., little immunity ) against the toxin. If the individual is immune to diphtheria, the antibody in the system will neutralize the toxin and no skin reaction will occur.
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