anabolic steroid ăn˝əbŏl´ĭk stĕr´oid, stĭr´– [key] or androgenic steroidăn˝drōjĕn´ĭk [key], any of a group of synthetic derivatives of testosterone that promote muscle and bone growth. Used to treat uncontrolled weight loss in wasting diseases, anabolic steroids have also been taken by bodybuilders and athletes seeking increased muscle mass, strength, and stamina. Such use is banned by the International Olympic Committee and other governing bodies in sports, but not all sports test for steroids. Major League Baseball did not test for steroids until 2003, when random testing returned positive results on more than 5% of the players tested, and the National Hockey League still does not test. Under a 1988 federal law it is illegal to distribute anabolic steroids for nontherapeutic uses, and in 1991 they joined other abused drugs as controlled substances. Nonetheless, a precursor hormone called dehydroepiandrosterone (DHEA), which can convert to testosterone in the body, is available as a dietary supplement without a prescription. Abuse of anabolic steroids may lead to elevated cholesterol levels, liver disease, blood clots leading to heart attack or stroke, increased aggressiveness and irritability, and, in adolescents, permanent stunting of growth. See also steroids.
The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2012, Columbia University Press. All rights reserved.
See more Encyclopedia articles on: Pharmacology