Medici, Francesco de'

Medici, Francesco de' fränchās´kō dā mĕ´dĭchē, Ital. mā´dēchē [key], 1541–87, grand duke of Tuscany (1574–87); son and successor of Cosimo I de' Medici . In his reign the decline of the Medici family began. He allowed the Austrian and Spanish branches of the house of Hapsburg to establish a virtual protectorate over his dominion, devoting himself to alchemy and other nonpolitical pursuits. He first married Joanna, daughter of Holy Roman Emperor Ferdinand I , and then, after Joanna's death, Bianca Capello . His daughter by the first marriage was Marie de' Medici , queen of Henry IV of France. Francesco was succeeded by his brother, Ferdinand I de' Medici .

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