Breadcrumb Home > Dictionary > Index T transubstantiation: Meaning and Definition of Find definitions for: tran•sub•stan•ti•a•tion Pronunciation: (tran"sub-stan"shē-ā'shun), [key] — n. the changing of one substance into another. the changing of the elements of the bread and wine, when they are consecrated in the Eucharist, into the body and blood of Christ (a doctrine of the Roman Catholic Church). Cf. transignification. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: transubstantiation (Thesaurus) transubstantiate transudation ✖ Related Content Daily Word Quiz: deracinate Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language