Breadcrumb Home > Dictionary > Index O Owensboro: Meaning and Definition of Find definitions for: Ow•ens•bor•o Pronunciation: (ō'unz-bûr"ō, -bur"ō), [key] — n. a city in NW Kentucky, on the Ohio River. 54,450. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: owensboro (Thesaurus) Owens Owen Sound ✖ Related Content Daily Word Quiz: tautology Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language