Breadcrumb Home > Dictionary > Index H Hampton Roads: Meaning and Definition of Find definitions for: Hamp'ton Roads' Pronunciation: [key] a channel in SE Virginia between the mouth of the James River and Chesapeake Bay: battle between the Monitor and the Virginia 1862. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. Hampton hamster ✖ Related Content Daily Word Quiz: careening Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language