Breadcrumb Home > Dictionary > Index C cheerio: Meaning and Definition of Find definitions for: cheer•i•o Pronunciation: (chēr'ē-ō", chēr"ē-ō'), [key] — interj., n., pl. cheer•i•os. —interj. good-bye; good-bye and good luck. (used as a toast to one's drinking companions.) —n. a good-bye or farewell. a toast of “cheerio!” Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: cheerio (Thesaurus) cheerful cheerlead TrendingHere are the facts and trivia that people are buzzing about. Biographies: Notable Jewish Religious Leaders Current Events This Week: September 2023 Hispanic Population and the 2010 U.S. Census Preamble of the United Nations Charter The Jewish Calendar ✖ Related Content Daily Word Quiz: bildungsroman Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language