Breadcrumb Home > Dictionary > Index B botfly: Meaning and Definition of Find definitions for: bot•fly Pronunciation: (bot'flī"), [key] — pl. -flies. any of several flies of the families Oestridae, Gasterophilidae, and Cuterebridae, the larvae of which are parasitic in the skin or other parts of various mammals. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: botfly (Thesaurus) botel both ✖ Related Content Daily Word Quiz: acronym Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language