The phenomenon of parthenogenesis was discovered in the 18th cent. by Charles Bonnet . In 1900, Jacques Loeb accomplished the first clear case of artificial parthenogenesis when he pricked unfertilized frog eggs with a needle and found that in some cases normal embryonic development ensued. Artificial parthenogenesis has since been achieved in almost all major groups of animals, although it usually results in incomplete and abnormal development. Numerous mechanical and chemical agents have been used to stimulate unfertilized eggs. In 1936, Gregory Pincus induced parthenogenesis in mammalian (rabbit) eggs by temperature change and chemical agents. No successful experiments with human parthenogenesis have been reported.
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