Breadcrumb Home > Dictionary > Index M metathesis: Meaning and Definition of Find definitions for: me•tath•e•sis Pronunciation: (mu-tath'u-sis), [key] — pl. -ses the transposition of letters, syllables, or sounds in a word, as in the pronunciationfor comfortable or (aks) for ask. See Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: metathesis (Thesaurus) metatherian metathesize ✖ Related Content Daily Word Quiz: spectral Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language