Breadcrumb Home > Dictionary > Index L loathsome: Meaning and Definition of Find definitions for: loath•some Pronunciation: (lō'sum, lōth'-), [key] — adj. causing feelings of loathing; disgusting; revolting; repulsive: a loathsome skin disease. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: loathsome (Thesaurus) loathly loaves ✖ Related Content Daily Word Quiz: hortatory Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language