Breadcrumb Home > Dictionary > Index I irk: Meaning and Definition of Find definitions for: irk Pronunciation: (ûrk), [key] — v.t. to irritate, annoy, or exasperate: It irked him to wait in line. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: irk (Thesaurus) iritis irksome ✖ Related Content Daily Word Quiz: rococo Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language