Breadcrumb Home > Dictionary > Index C comedo: Meaning and Definition of Find definitions for: com•e•do Pronunciation: (kom'i-dō"), [key] — pl. com•e•dos, com•e•do•nes a thickened secretion plugging a duct of the skin, esp. of a sebaceous gland; blackhead. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: comedo (Thesaurus) comedist comedown TrendingHere are the facts and trivia that people are buzzing about. Chinese New Year History, Meaning, and Celebrations Current Events This Week: February 2024 Valentine's Day Valentine's Day History Mardi Gras 30 "Charlie and the Chocolate Factory" Quotes ✖ Related Content Daily Word Quiz: apotheosis Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language