Breadcrumb Home > Dictionary > Index C centrosome: Meaning and Definition of Find definitions for: cen•tro•some Pronunciation: (sen'tru-sōm"), [key] — n. Cell Biol. a small region near the nucleus in the cell cytoplasm, containing the centrioles. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: centrosome (Thesaurus) centromere centrosphere ✖ Related Content Daily Word Quiz: restive Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language