mole, in chemistry, a quantity of particles of any type equal to Avogadro's number, or 6.021023 particles. One gram-molecular weight of any molecular substance contains exactly one mole of molecules. The term mole is often used in place of gram-molecular weight; e.g., one speaks of 18 grams of water as one mole of water rather than as one gram-molecular weight of water. The mole is a unit in the International System of Units (SI).
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