Cholula chōlo͞o´lä [key] or Cholula de Rivadabia chōlo͞o´lä ᵺā rē˝vädäv´yä [key], city (1990 pop. 53,673), Puebla state, E central Mexico. The site of the famous Teocali de Cholula, a pre-Columbian pyramid of great antiquity, the city was an old Toltec center and, when the Spanish came, was an Aztec sacred city devoted to the worship of Quetzalcoatl . Suspecting native insurrection, Hernán Cortés destroyed the city in 1519; from 5,000 to 10,000 people were killed in the massacre of Cholula. Cortés then vowed to build a church for each of the 400 Aztec shrines; 70 were in fact built, one atop the pyramid. The picturesque city remains a place of pilgrimage and attracts many tourists.

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