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Meaning of tachyphylaxis

tach•y•phy•lax•is

Pronunciation: (tak"u-fi-lak'sis), [key]
— n.
  1. immediate, temporary immunization against the effects of injection of a toxic extract owing to previous small injections of the same extract.
  2. a decreased response to a medicine given over a period of time so that larger doses are required to produce the same response.
Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease.