Breadcrumb Home > Dictionary > Index E exterminate: Meaning and Definition of Find definitions for: ex•ter•mi•nate Pronunciation: (ik-stûr'mu-nāt"), [key] — -nat•ed, -nat•ing. to get rid of by destroying; destroy totally; extirpate: to exterminate an enemy; to exterminate insects. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease. See also: exterminate (Thesaurus) exteriorize exterminator ✖ Related Content Daily Word Quiz: evanescent Analogy of the Day: Today’s Analogy Frequently Misspelled Words Frequently Mispronounced Words Easily Confused Words Writing & Language