1. Mother, informally
2. The Hawkeye State
3. Marine Mollusk
4. The Masses: ___ Polloi
5. O.J.'s pal
6. Omaha's locale on an env.
7. Credit transfer system
8. It'll make "trifying" thrilling
9. Classy Car
10. Atop
11. Father, informally
13. Light-headed
15. The Medici family dominated it, and it dominated the Renaissance
18. When doubled, it means "bye-bye!"
19. "The ___ of Moses": Creation by Sandro Botticelli (b.1445 - d.1510)
21. ___-shucks!
22. She had a hit with "Don't Wanna Lose You" (Initials)
23. Gershwin the Lyricist
24. Chuck Heston's controversial gr.
25. Gilligan's boat: "___ Minnow"
26. Atomic #52
29. Dessert menu selection
30. Character depicted in Raphael's famous fresco "The School of Athens"
32. Renaissance masterpiece "Madonna of the Goldfinch", for example
33. "Small" in Strasbourg
34. Bronze on the Beach
37. You: Français
38. Renaissance masterpiece: "Saints ___ Angels"
40. "The Shaggy ___" (1976)
41. Sports peg
42. Acronym used on a questionnaire when a particular question isn't relevant
43. Business card abbr.
44. It'll bring "tiate" into being
45. Certain face shapes
50. Renaissance masterpiece: "Madonna and ___"
51. Not hers
53. Summer hrs. in VA
55. Psyche Part
56. Negative reply
59. Initials of the actress who co-starred in "Yentl" (1983)
60. It'll make "cal" outspoken
62. "The Second Sex" (1953) author: Simone ___ Beauvoir
63. It'll turn "ngs" into nest eggs
64. Chieftain
65. Insincere talk
66. ___ even keel
67. Lima is its capital
71. Shoe width Size
72. Blood Bank acronym
74. Exercise device: "___ Rocker"
75. Book section, for short
76. Greek Mythology: To protect her from Hera's jealousy, Zeus turned her into a heifer
78. Eliot of "The Waste Land" (1922)