| No | Date | Opponent, location | Result |
|---|
| 1 | 3/6/85 | Hector Mercedes, Albany, N.Y. | KO 1 |
| 2 | 4/10/85 | Trent Singleton, Albany, N.Y. | TKO 1 |
| 3 | 5/23/85 | Don Halpin, Albany, N.Y. | KO 4 |
| 4 | 6/20/85 | Rick Spain, Atlantic City | KO 1 |
| 5 | 7/11/85 | John Anderson, Atlantic City | TKO 2 |
| 6 | 7/19/85 | Larry Sims, Poughkeepsie, N.Y. | KO 3 |
| 7 | 8/15/85 | Lorenzo Canady, Atlantic City | TKO 1 |
| 8 | 9/5/85 | Michael Johnson, Atlantic City | KO 1 |
| 9 | 10/9/85 | Donnie Long, Atlantic City | KO 1 |
| 10 | 10/25/85 | Robert Colay, Atlantic City | KO 1 |
| 11 | 11/1/85 | Sterling Benjamin, Latham, N.Y. | TKO 1 |
| 12 | 11/13/85 | Eddie Richardson, Houston | KO 1 |
| 13 | 11/22/85 | Conroy Nelson, Latham, N.Y. | KO 2 |
| 14 | 12/6/85 | Sammy Scaff, New York City | KO 1 |
| 15 | 12/27/85 | Mark Young, Latham, N.Y. | KO 1 |
| 16 | 1/10/86 | Dave Jaco, Albany, N.Y. | TKO 1 |
| 17 | 1/24/86 | Mike Jameson, Atlantic City | TKO 5 |
| 18 | 2/16/86 | Jesse Ferguson, Troy, N.Y. | TKO 6 |
| 19 | 3/10/86 | Steve Zouski, Uniondale, N.Y. | KO 3 |
| 20 | 5/3/86 | James Tillis, Glens Falls, N.Y. | Wu 10 |
| 21 | 5/20/86 | Mitchell Green, New York City | Wu 10 |
| 22 | 6/13/86 | Reggie Gross, New York City | TKO 1 |
| 23 | 6/28/86 | William Hosea, Troy, N.Y. | KO 1 |
| 24 | 7/11/86 | Lorenzo Boyd, Swan Lake, N.Y. | KO 2 |
| 25 | 7/26/86 | Marvis Frazier, Glens Falls, N.Y. | KO 1 |
| 26 | 8/17/86 | Jose Ribalta, Atlantic City | TKO 10 |
| 27 | 9/6/86 | Alfonzo Ratliff, Las Vegas | KO 2 |
| 28 | 11/22/86 | Trevor Berbick, Las Vegas | KO 2 |
| | | (won WBC heavyweight title) |
| 29 | 3/7/87 | Bonecrusher Smith, Las Vegas | Wu 12 |
| | | (won WBA heavyweight title) |
| 30 | 5/30/87 | Pinklon Thomas, Las Vegas | TKO 6 |
| 31 | 8/1/87 | Tony Tucker, Las Vegas | Wu 12 |
| | | (won IBF heavyweight title) |
| 32 | 10/16/87 | Tyrell Biggs, Atlantic City | TKO 7 |
| 33 | 1/22/88 | Larry Holmes, Atlantic City | KO 4 |
| 34 | 3/21/88 | Tony Tubbs, Tokyo | TKO 2 |
| 35 | 6/27/88 | Michael Spinks, Atlantic City | KO 1 |
| 36 | 2/25/89 | Frank Bruno, Las Vegas | TKO 5 |
| 37 | 7/21/89 | Carl Williams, Atlantic City | TKO 1 |
| 38 | 2/10/90 | Buster Douglas, Tokyo | KO by 10 |
| | | (lost world heavyweight title) |
| 39 | 6/16/90 | Henry Tillman, Las Vegas | KO 1 |
| 40 | 12/8/90 | Alex Stewart, Atlantic City | TKO 1 |
| 41 | 3/18/91 | Razor Ruddock, Las Vegas | TKO 7 |
| 42 | 6/28/91 | Razor Ruddock, Las Vegas | Wu 12 |
| 43 | 8/19/95 | Peter McNeeley, Las Vegas | W disq. 1 |
| | | (first fight since release from prison) |
| 44 | 12/16/95 | Buster Mathis Jr., Philadelphia | KO 3 |
| 45 | 3/16/96 | Frank Bruno, Las Vegas | TKO 3 |
| | | (won WBC heavyweight title) |
| 46 | 9/7/96 | Bruce Seldon, Las Vegas | TKO 1 |
| | | (won WBA heavyweight title) |
| 47 | 11/9/96 | Evander Holyfield, Las Vegas | TKO by 11 |
| | | (lost WBA heavyweight title) |
| 48 | 6/28/97 | Evander Holyfield, Las Vegas | L disq 3 |
| | | (disqualified for biting Holyfield's ears) |
| 49 | 1/16/99 | Frans Botha, Las Vegas | KO 5 |
| 50 | 10/23/99 | Orlin Norris, Las Vegas | NC* |
| 51 | 1/29/00 | Julius Francis, Manchester, ENG | TKO 2 |
| 52 | 6/24/00 | Lou Savarese, Glasgow, SCOT | TKO 1 |
| 53 | 10/20/00 | Andrew Golota, Auburn Hills, MI | NC* |
| 54 | 10/13/00 | Brian Nielsen, Copenhagen, DEN | TKO 7 |
*The Tyson-Norris bout was ruled a no-contest after Norris hurt his knee and could not continue following a off-the-clinch-punch from Mike Tyson. The Tyson-Golota bout was initially ruled a third-round TKO win for Tyson but was later ruled a no contest because Tyson refused to take a pre-fight drug test and then tested positive for marijuana in a post-fight urine test.
