C. sativa grows as a common weed in many parts of the world, and drug preparations vary widely in potency according to climate, cultivation, and method of preparation. Mexico, Paraguay, and the United States are the top marijuana-producing nations worldwide. C. indica is a shorter, hardier variety with rounded blue-green leaves, grown in Afghanistan for hashish. Most marijuanas grown in the United States since the late 1980s are hybrids of the two and yield a much more potent product than the marijuana of the past. The resin found on flower clusters and top leaves of the female plant is the most potent drug source and is used to prepare hashish, the highest grade of cannabis. The bud of the female plant, called sinsemilla, is the part most often smoked as marijuana.
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