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morphine

morphine, principal derivative of opium, which is the juice in the unripe seed pods of the opium poppy, Papaver somniferum. It was first isolated from opium in 1803 by the German pharmacist F. W. A. Sertürner, who named it after Morpheus, the god of dreams. Given intravenously, it is still considered the most effective drug for the relief of pain.

See also drug addiction and drug abuse.

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The Columbia Electronic Encyclopedia, 6th ed. Copyright © 2007, Columbia University Press. All rights reserved.

More on morphine from Infoplease:

morphine: meaning and definitions - morphine: Definition and Pronunciation
morphine: History - History Morphine was first used medicinally as a painkiller and, erroneously, as a cure for opium ...
morphine: Bibliography - Bibliography See publications of the Drugs & Crime Data Center and Clearinghouse, the Bureau of ...
morphine: Effects and Uses - Effects and Uses Morphine, a narcotic, acts directly on the central nervous system. Besides ...
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Postoperative Analgesia and Recovery Course After Major Colorectal Surgery in Elderly Patients: A Randomized Comparison Between Intrathecal Morphine and Intravenous PCA Morphine (Regional Anesthesia and Pain Medicine)

IV to po morphine conversion ratio of 1:3 achieves pain control.(Neurology)(intravenous)(Clinical report) (Internal Medicine News)

Met-enkephalin involvement in morphine-modulated peritonitis in Swiss mice. (Mediators of Inflammation)

Less morphine may be more.(combination of morphine and naltrexone may provide greater pain relief)(Brief Article) (Science News)

New data cast doubt on IV morphine for ACS.(acute coronary syndromes )(intravenous morphine ) (Internal Medicine News)

No Evidence for Analgesic Effect of Intra-articular Morphine After Knee Arthroscopy: A Qualitative Systematic Review (Regional Anesthesia and Pain Medicine)

Expression of opioid receptor-like 1 (ORL1) & mu opioid receptors in the spinal cord of morphine tolerant mice (Indian Journal of Medical Research)

Evaluation of peripheral morphine analgesia for lumpectomy and axillary node dissection: A randomized, double-blind, placebo-controlled study (Regional Anesthesia and Pain Medicine)

Prehospital administration of morphine for isolated extremity injuries: A change in protocol reduces time to medication (Prehospital Emergency Care)

Once-daily morphine shows greater improvement than oxycodone BID for chronic back pain (Formulary)

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